Rosuvastatin Again Linked With Risks to Kidneys

Rosuvastatin for cholesterol lowering was associated with slightly greater risks for kidney harm than atorvastatin, risks that were greater at higher-dose levels, in a large retrospective cohort study.

The most potent statin on the market, rosuvastatin has been linked with excess risk for kidney damage compared with atorvastatin in case reports and small trials, but there has been little surveillance of the issue following its approval in 2003.

The current analysis “is one of the first and largest real-world studies” examining rosuvastatin versus atorvastatin for risk for hematuria, proteinuria, and kidney failure with replacement therapy — dialysis or transplantation — across a range of estimated glomerular filtration rates (eGFR) in a heterogeneous population, the researchers write.



Click here to continue reading:

Παλαιότερα άρθρα